Smart Nutri, Nano Bone - 60 Capsules (BUY 2, GET 1 FREE!)

Smart Nutri, Nano Bone - 60 Capsules (BUY 2, GET 1 FREE!)
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Osteoporosis is a condition of decreased bone density. It affects one in six women and one in eight men over the age of fifty and is most common among post-menopausal women. Osteoporosis is often the cause of many health complications, as it progresses silently and unnoticed for years. Only after years of bone loss do signs and symptoms appear, such as pain, spinal deformity, and fractures. 

An individual’s peak bone mass occurs between the ages of twenty and thirty. Bones reach their maximum density and strength during this time. After peak bone mass is reached, bone rebuilding gradually wanes. For women, the greatest bone loss occurs in the years immediately after menopause when estrogen levels decline. Bone continually renews itself by remodeling – building up and breaking down. For this to occur, bone needs certain nutrients.

NANO CALCIUM PLUSTMis micronized calcium based on unique, patented technology that can pulverize calcium into nano-sized powder (0.3 μm [300 nanometers] ~ 15 μm [15,000 nanometers) without changing the integrity of the original nutrients. Lab and human tests revealed solid bioavailability effects never been seen in traditional calcium.  


  • Build strong bones and teeth
  • Prevent osteoporosis 



NC-518(nano calcium): Our Nano Calcium (NC-518) is very fine, but remains larger than milk particles. The key difference between milk, the touted source of calcium, and our NC-518, has to do with bioavailability. Milk, though very fine in particle size, has an absorption rate of only about 40%; traditional calcium’s absorption rate is only 2~10%. Further, bioavailability is not necessarily proportional to increased absorption rate. For example, ionized calcium, known to be the best source for calcium intake, has a nearly 100% absorption rate and solubility, but is ineffective in bioavailability, as our clinical study will show below. 

That NC-518 is physically finer than traditional calcium carbonate contributes to its high bioavailability, but the main reason behind this quality lies at the core of our technology. The existing Zet Mill/Ball Mill (bottom-up) method employs a process that relies on the addition of water to the ingredients. Yet this use of water creates a complication; it poses the risk of oxidizing, and thus sacrificing, the core nutrients, which necessitates a subsequent and inefficient process of re-drying.

 Our patented 4D top-down Mill technology (US Patent 7347393 - Nano grinding mill – Issued on March 25, 2008) does not use water, and the whole process is executed in a dry environment. In the pulverizing process, temperature, moisture, and pressure levels are completely controlled and monitored. Referred to as the ‘Ultra Precision Grinding Energy Management System,’ our technology imposes no heat and involves no metallic friction, cutting, or chafing. The lack of heat means that the original integrity of the nutrients is preserved; similarly, the non-abrasive technology of the metallic devices protects the nutrients from contamination. 

* NC-518® wins 2011 IFT Food Expo Innovation Award! 

Vitamin D: Vitamin D deficiency causes osteomalacia (called rickets when it occurs in children).Beyond that, low serum vitamin D levels have been associated with falls, and low bone mineral density. For bone health, vitamin D and calcium go hand in hand, because the vitamin must be present for calcium to be absorbed from the digestive tract.

Human Clinical Study I.

Open-label, Randomized controlled trial


Study Result

  • Significant improvement of BMD T-score (nearly 10% increase) 
  • The longer they take, the increase in BMD is more pronounced

*Source:  Attached please find (file name: [NC-518] Clinical Trial I.pdf)


Human Clinical Study II.

Double-blind, Placebo-controlled trial





  • In the non-bisphosphonate group of this study, NC-518® showed 2% T-score increase in BMD in 4 months. 
  • The significant improvement in T-scores in those who took NC-518® rather than Caltrate® is due to NC-518®’s better absorption and bioavailability.


*Source:  Attached please find (file name: [NC-518] Clinical Trial II.pdf)
*Natural Products Insider’s Article about NC-518:





Frequently Asked Questions

Q.  Why is calcium so important?

A. Calcium is an essential mineral found in great abundance in the body. Ninety-nine percent of all the calcium in the body is found in the bones and teeth. The remaining one percent is in the blood. Calcium plays important roles in nerve conduction, muscle contraction, and blood clotting. If calcium levels in the blood drop below normal, calcium will be taken from bone and put into the blood in order to maintain blood calcium levels. Therefore, it is important to consume enough calcium to maintain adequate blood and bone calcium levels.


Q.  How much calcium do I need? 

A. The National Institute of Health Consensus Conference and The National Osteoporosis Foundation support a higher calcium intake of 1,500 milligrams per day for postmenopausal women not taking estrogen and adults 65 years or older.



Q. What is osteoporosis?

A.  Osteoporosis is a condition in which the bones become fragile and brittle, leading to a higher risk of fractures (breaks or cracks) than in normal bone.Osteoporosis occurs when bones lose minerals, such as calcium, more quickly than the body can replace them, leading to a loss of bone thickness (bone mass or density). As a result, bones become thinner and less dense, so that even a minor bump or accident can cause serious fractures. These are known as fragility or minimal trauma fractures.

Any bone can be affected by osteoporosis, but the most common sites are bones in the hip, spine, wrist, ribs, pelvis and upper arm. Osteoporosis usually has no signs or symptoms until a fracture happens - this is why osteoporosis is often called the 'silent disease'.

Fractures due to osteoporosis (osteoporotic fractures) can lead to changes in posture (eg developing a stoop or Dowager's hump in your back), muscle weakness, loss of height and bone deformity of the spine. Fractures can lead to chronic pain, disability, loss of independence and even premature death.


Q. Who gets osteoporosis?

A.  Osteoporosis affects both women and men. Women are at a greater risk of developing osteoporosis than men, mainly due to the rapid decline in oestrogen levels after menopause. Oestrogen is an important hormone for maintaining healthy bones. When oestrogen levels decrease, the bones lose calcium (and other minerals) at a much faster rate - bone loss is approximately 1% - 5% per year after menopause. Men also lose bone as they age, but their bone mass generally remains adequate until much later in life. However, certain risk factors such as reduced calcium intake and low levels of vitamin D can increase age related bone loss. Although osteoporotic fractures are less common in men than in women, when they occur, these fractures are associated with higher disability and death than in women.


Q.  Are osteoarthritis and osteoporosis the same thing?

A.  No. Although they both contain the term 'osteo', which means bone, they are quite different conditions. Osteoarthritis is a degenerative joint disease and involves deterioration of the joint surfaces (the cartilage covering the ends of the bones), leading to pain and stiffness in the joints. Osteoporosis involves thinning of the bone itself, making it weak, brittle and more likely to fracture.


Q.  What are the risk factors of osteoporosis?


1. Your family history: Any family history of osteoporosis and fractures 

2. Your medical history: Certain conditions and medications can increase your risk of osteoporosis

  • Cortico-steroids (commonly used for Asthma)
  • Rheumatoid arthritis
  • Over-active thyroid or parathyroid glands
  • Coeliac disease and other chronic gut conditions
  • Chronic liver or kidney disease

The following symptoms may also indicate an increased risk of osteoporosis. 

3. For men

  • Impotence
  • Lack of libido
  • Other symptoms of low testosterone levels 

4. For women:

  • If your period has stopped for 6-12 consecutive months (excluding pregnancy, menopause or hysterectomy)
  • If you experience early menopause 

5. Your lifestyle:

  • Smoking
  • Excessive alcohol consumption
  • Diet lacking in calcium
  • Lack of sunlight exposure, which may cause vitamin D deficiency
  • Sedentary lifestyle over many years


Q.  How is osteoporosis diagnosed? 

A. Osteoporosis is diagnosed by a bone density test (medical name - Dual-energy X-ray Absorptiometry; DXA). It is a short, painless scan that measures the density (strength) of your bones, usually at the hip and spine. The result from this test is called a T-score. Your GP will first assess your risk factors for osteoporosis, which include your age, medical history and lifestyle factors, before referring you for a test.


Q. What is Bone Mineral Density (BMD)? 

A.  Bone density (or bone mineral density) is a medical term normally referring to the amount of mineral matter per squarecentimeter of bones. Bone density (or BMD) is used in clinical medicine as an indirect indicator of osteoporosis and fracture risk.This medical bone density is not the true physical "density" of the bone, which would be computed as mass per volume.  

Bonemass refers to the weight of the skeleton. Bone density refers to theratio of weight to the volume or area of the bones. The basic idea isthat heavier bones will be stronger bones. The child or adult’s age,height and degree of physical maturity are important factors inmeasuring and understanding bone mineral density (BMD). 


Q.  How to read Bone Mineral Density (BMD) test results? What the numbers mean? 

A.  A bone density test will give you a T-score. The result will be in the range of: 

  • Normal;
  • Osteopenia (low bone density); or
  • Osteoporosis 

If the test shows normal

You have normal bone density. Exercise, adequate calcium intake and vitamin D are all important factors for maintaining bone health.


If the test shows osteopenia (low bone density)

Your doctor may recommend lifestyle changes to reduce risk factors that can affect bone health. Your doctor will also recommend a follow-up test in 1-2 years to monitor your bone density.


If the test shows osteoporosis

This means your bone density is low and at risk of fracture. Your doctor will probably recommend you start treatment to stop further bone loss and prevent fractures. Lifestyle changes will also be recommended. A follow-up test is commonly conducted in a year to monitor your bone density and the effectiveness of the treatment.


Q.  What is osteoporosis medicine? 

A.  There are several types of medication, but every medication has possible side effects and this is no less true for osteoporosis medications!.

  • Bisphosphonates (trade name: Fosamax, Actonel, Didrocal, Aclasta)– see below
  • Hormone Replacement Therapy (HRT) - Heart disease, Blood clots, Strokes, Breast cancer
  • Selective Oestrogen Receptor Modulators (trade name: Evista) - Hot flashes, Leg cramps, Fluid retention, Flu-like syndrome (mild)


The FDA sent out a nationwide announcement about "the potential side effects of osteoporosis drugs like Fosamax ." the agency "said in their announcement...physicians need to watch for the possibility of possible risk of femur fractures. And this didn't just apply to Fosamax, this applied to all four drugs that are in this group Fosamax, Actonel , Boniva , and Reclast" 


Q.  And how long should I take medication for?

A.  To get full benefit from your prescription medications, it is important to take them exactly as directed and for as long as your doctor prescribes. Unfortunately, many people stop treatment within 2 years, which is common with long-term medications. This means you do not get the full benefit of taking the drugs. 


Q.  Why is NANO CALCIUM PLUS so different? 

A.  Calcium supplements in the market have caused much dissatisfaction due to their negative side effects such as gas, constipation, and upset stomach. The absorption and bioavailability of these products have also been questioned. Our NANO CALCIUM PLUSis claimed to be highly absorbable, particularly due to its formation, which is based on unique, patented technology. In comparison to other technologies that use water and high heat, which results in a loss of core nutrients and decreased product efficacy, the calcium produced by this unique pulverizing technology is micron-sized (0.3um – 10um) and therefore more effective. While its tiny size significantly increases its absorption, it is the intense activation of zinc via the patented ebonite charging process that maximizes the bioavailability of this calcium in the body.


Q.  What is the meaning of the bioavailability? 

A.  The degree to which a drug or other substance becomes available to the target tissue after administration.


Q.  How effective is NANO CALCIUM PLUS? 

A.  As a result of 1st clinical trial, the average pre-treatment BMD T-score of -2.2 increased to -1.32, an increase of 0.88, or nearly 10%. (1 SD difference in a T-score is equal to a 10-15% decrease in bone density. For example, a person with a T-score of -2.5 has a 10-15% lower BMD than a person with a T-score of -1.5.) This is a very significant improvement!

 The 2nd clinical trial result reveals that NANO CALCIUM PLUSshowed 2% T-score increase in BMD in 4 months.

These results are because of NANO CALCIUM PLUS’s better absorption and bioavailability.


Q.  Who should take NANO CALCIUM PLUS? 

A.Calcium and calcium supplements can play a bone-saving role in your life, no matter how old you are. Typically, it is thought that children need calcium for their growing bones, but many don’t realize that bone growth doesn’t stop there. As you age, calcium becomes even more important to build and maintain bones and prevent osteoporosis.